โœจ Here we are again! โœจ
This time with a special request from clients and followers who want help navigating diabetes mellitus and the new medications on the market.

ย Episode 3aย kicks off our exploration ofย Bexaglifozin, with a second episode dedicated toย Velaglifozinย coming soon!
๐Ÿ”— You can access:
A summaryย for quick insights: see below
A detailed discussionย here:



๐Ÿ“š Study Summary
๐˜š๐˜ข๐˜ง๐˜ฆ๐˜ต๐˜บ ๐˜ข๐˜ฏ๐˜ฅ ๐˜Œ๐˜ง๐˜ง๐˜ฆ๐˜ค๐˜ต๐˜ช๐˜ท๐˜ฆ๐˜ฏ๐˜ฆ๐˜ด๐˜ด ๐˜ฐ๐˜ง ๐˜ต๐˜ฉ๐˜ฆ ๐˜š๐˜ฐ๐˜ฅ๐˜ช๐˜ถ๐˜ฎ-๐˜Ž๐˜ญ๐˜ถ๐˜ค๐˜ฐ๐˜ด๐˜ฆ ๐˜Š๐˜ฐ๐˜ต๐˜ณ๐˜ข๐˜ฏ๐˜ด๐˜ฑ๐˜ฐ๐˜ณ๐˜ต๐˜ฆ๐˜ณ ๐˜๐˜ฏ๐˜ฉ๐˜ช๐˜ฃ๐˜ช๐˜ต๐˜ฐ๐˜ณ ๐˜‰๐˜ฆ๐˜น๐˜ข๐˜จ๐˜ญ๐˜ช๐˜ง๐˜ญ๐˜ฐ๐˜ป๐˜ช๐˜ฏ ๐˜ช๐˜ฏ ๐˜Š๐˜ข๐˜ต๐˜ด ๐˜•๐˜ฆ๐˜ธ๐˜ญ๐˜บ ๐˜‹๐˜ช๐˜ข๐˜จ๐˜ฏ๐˜ฐ๐˜ด๐˜ฆ๐˜ฅ ๐˜ธ๐˜ช๐˜ต๐˜ฉ ๐˜‹๐˜ช๐˜ข๐˜ฃ๐˜ฆ๐˜ต๐˜ฆ๐˜ด ๐˜”๐˜ฆ๐˜ญ๐˜ญ๐˜ช๐˜ต๐˜ถ๐˜ด
๐˜๐˜ข๐˜ฅ๐˜ฅ ๐˜ฆ๐˜ต ๐˜ข๐˜ญ., ๐˜‘ ๐˜๐˜ฆ๐˜ต ๐˜๐˜ฏ๐˜ต๐˜ฆ๐˜ณ๐˜ฏ ๐˜”๐˜ฆ๐˜ฅ. 2023 ๐˜”๐˜ข๐˜บ-๐˜‘๐˜ถ๐˜ฏ;37(3):915-924. ๐˜ฅ๐˜ฐ๐˜ช: 10.1111/๐˜ซ๐˜ท๐˜ช๐˜ฎ.16730.
๐Ÿ’กย Background
This study evaluates the safety and effectiveness of bexagliflozin in cats newly diagnosed with diabetes mellitus.
๐Ÿ’ก Aim
1๏ธโƒฃ Assess the safety profile of bexagliflozin
2๏ธโƒฃ Evaluate its efficacy in improving glycemic control
๐Ÿ’กย Materials and Methods
๐Ÿพ Newly diagnosed diabetic cats confirmed via clinical signs, hyperglycemia, and glucosuria
๐Ÿ’Š Cats received oral bexagliflozin, with monitoring for blood glucose, fructosamine levels, clinical signs, and adverse events
๐Ÿ’กย Key Findings
โœ”๏ธย ๐˜Œ๐˜ง๐˜ง๐˜ช๐˜ค๐˜ข๐˜ค๐˜บ:ย Improved glycemic control inย 84% of cats
โœ”๏ธย ๐˜Š๐˜ญ๐˜ช๐˜ฏ๐˜ช๐˜ค๐˜ข๐˜ญ ๐˜š๐˜ช๐˜จ๐˜ฏ๐˜ด:ย Substantial improvement in diabetes-related signs (polyuria, polydipsia, polyphagia)
โœ”๏ธย ๐˜š๐˜ข๐˜ง๐˜ฆ๐˜ต๐˜บ:ย Generally well-tolerated; some adverse events (vomiting, diarrhea, anorexia, lethargy, dehydration) noted
โš ๏ธย ๐˜š๐˜ฆ๐˜ณ๐˜ช๐˜ฐ๐˜ถ๐˜ด ๐˜ˆ๐˜ฅ๐˜ท๐˜ฆ๐˜ณ๐˜ด๐˜ฆ ๐˜Œ๐˜ท๐˜ฆ๐˜ฏ๐˜ต๐˜ด:ย Rare cases of diabetic ketoacidosis and euglycemic diabetic ketoacidosis emphasize the need for close monitoring
๐Ÿ’ฌย Conclusion
Bexagliflozin is a promising option for newly diagnosed diabetic cats, but careful patient selection and monitoring are critical.

๐˜‹๐˜ช๐˜ด๐˜ค๐˜ญ๐˜ข๐˜ช๐˜ฎ๐˜ฆ๐˜ณ:
Please remember this is a brief summary. For a comprehensive understanding of the study’s findings and implications, please refer to the full-text article: doi: 10.1111/jvim.16730

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