โจ Here we are again! โจ
This time with a special request from clients and followers who want help navigating diabetes mellitus and the new medications on the market.
ย Episode 3aย kicks off our exploration ofย Bexaglifozin, with a second episode dedicated toย Velaglifozinย coming soon!
๐ You can access:
A summaryย for quick insights: see below
A detailed discussionย here:
๐ Study Summary
๐๐ข๐ง๐ฆ๐ต๐บ ๐ข๐ฏ๐ฅ ๐๐ง๐ง๐ฆ๐ค๐ต๐ช๐ท๐ฆ๐ฏ๐ฆ๐ด๐ด ๐ฐ๐ง ๐ต๐ฉ๐ฆ ๐๐ฐ๐ฅ๐ช๐ถ๐ฎ-๐๐ญ๐ถ๐ค๐ฐ๐ด๐ฆ ๐๐ฐ๐ต๐ณ๐ข๐ฏ๐ด๐ฑ๐ฐ๐ณ๐ต๐ฆ๐ณ ๐๐ฏ๐ฉ๐ช๐ฃ๐ช๐ต๐ฐ๐ณ ๐๐ฆ๐น๐ข๐จ๐ญ๐ช๐ง๐ญ๐ฐ๐ป๐ช๐ฏ ๐ช๐ฏ ๐๐ข๐ต๐ด ๐๐ฆ๐ธ๐ญ๐บ ๐๐ช๐ข๐จ๐ฏ๐ฐ๐ด๐ฆ๐ฅ ๐ธ๐ช๐ต๐ฉ ๐๐ช๐ข๐ฃ๐ฆ๐ต๐ฆ๐ด ๐๐ฆ๐ญ๐ญ๐ช๐ต๐ถ๐ด
๐๐ข๐ฅ๐ฅ ๐ฆ๐ต ๐ข๐ญ., ๐ ๐๐ฆ๐ต ๐๐ฏ๐ต๐ฆ๐ณ๐ฏ ๐๐ฆ๐ฅ. 2023 ๐๐ข๐บ-๐๐ถ๐ฏ;37(3):915-924. ๐ฅ๐ฐ๐ช: 10.1111/๐ซ๐ท๐ช๐ฎ.16730.
๐กย Background
This study evaluates the safety and effectiveness of bexagliflozin in cats newly diagnosed with diabetes mellitus.
๐ก Aim
1๏ธโฃ Assess the safety profile of bexagliflozin
2๏ธโฃ Evaluate its efficacy in improving glycemic control
๐กย Materials and Methods
๐พ Newly diagnosed diabetic cats confirmed via clinical signs, hyperglycemia, and glucosuria
๐ Cats received oral bexagliflozin, with monitoring for blood glucose, fructosamine levels, clinical signs, and adverse events
๐กย Key Findings
โ๏ธย ๐๐ง๐ง๐ช๐ค๐ข๐ค๐บ:ย Improved glycemic control inย 84% of cats
โ๏ธย ๐๐ญ๐ช๐ฏ๐ช๐ค๐ข๐ญ ๐๐ช๐จ๐ฏ๐ด:ย Substantial improvement in diabetes-related signs (polyuria, polydipsia, polyphagia)
โ๏ธย ๐๐ข๐ง๐ฆ๐ต๐บ:ย Generally well-tolerated; some adverse events (vomiting, diarrhea, anorexia, lethargy, dehydration) noted
โ ๏ธย ๐๐ฆ๐ณ๐ช๐ฐ๐ถ๐ด ๐๐ฅ๐ท๐ฆ๐ณ๐ด๐ฆ ๐๐ท๐ฆ๐ฏ๐ต๐ด:ย Rare cases of diabetic ketoacidosis and euglycemic diabetic ketoacidosis emphasize the need for close monitoring
๐ฌย Conclusion
Bexagliflozin is a promising option for newly diagnosed diabetic cats, but careful patient selection and monitoring are critical.
๐๐ช๐ด๐ค๐ญ๐ข๐ช๐ฎ๐ฆ๐ณ:
Please remember this is a brief summary. For a comprehensive understanding of the study’s findings and implications, please refer to the full-text article: doi: 10.1111/jvim.16730